Departmental Publications 2015

Real-time analysis of the detailed sequence of cellular events in mAb-mediated complement-dependent cytotoxicity of B-cell lines and of chronic lymphocytic leukemia B-cells. Lindorfer MA, Cook EM, Tupitza JC, Zent CS, Burack R, de Jong RN, Beurskens FJ, Schuurman J, Parren PW, Taylor RP. Mol Immunol. 2015 Dec 12;70:13-23. doi: 10.1016/j.molimm.2015.12.007. PMID: 26690706

Preventing the Androgen Receptor N/C Interaction Delays Disease Onset in a Mouse Model of SBMA. Zboray L, Pluciennik A, Curtis D, Liu Y, Berman-Booty LD, Orr C, Kesler CT, Berger T, Gioeli D, Paschal BM, Merry DE. Cell Rep. 2015 Dec 15;13(10):2312-23. doi: 10.1016/j.celrep.2015.11.019. Epub 2015 Dec 7. PMID: 26673324

The molecular basis for flexibility in the flexible filamentous plant viruses. DiMaio F, Chen CC, Yu X, Frenz B, Hsu YH, Lin NS, Egelman EH. Nat Struct Mol Biol. 2015 Aug;22(8):642-4. doi: 10.1038/nsmb.3054. Epub 2015 Jul 13. PMID: 26167882

Combinatorial drug screening and molecular profiling reveal diverse mechanisms of intrinsic and adaptive resistance to BRAF inhibition in V600E BRAF mutant melanomas. Roller DG, Capaldo B, Bekiranov S, Mackey AJ, Conaway MR, Petricoin EF, Gioeli D, Weber MJ. Oncotarget. 2015 Dec 10. doi: 10.18632/oncotarget.6548. PMID: 26673621

Efficacy of Hybrid Tetrahydrobenzo[d]thiazole Based Aryl Piperazines D-264 and D-301 at D<sub>2</sub> and D<sub>3</sub> Receptors. Zhen J, Antonio T, Jacob JC, Grandy DK, Reith ME, Dutta AK, Selley DE. Neurochem Res. 2015 Dec 31.  PMID: 26718829

Initiation of replication in Xenopus egg extracts at a spatially defined origin. Lee KY, Dutta A. Cell Cycle. 2015 Aug 3;14(15):2391. doi: 10.1080/15384101.2015.1063306. Epub 2015 Jun 19. No abstract available.  PMID: 26091433

Environmental and chemotherapeutic agents induce breakage at genes involved in leukemia-causing gene rearrangements in human hematopoietic stem/progenitor cells. Thys RG, Lehman CE, Pierce LC, Wang YH. Mutat Res. 2015 Sep;779:86-95. doi: 10.1016/j.mrfmmm.2015.06.011. Epub 2015 Jun 27. PMID: 26163765

 A Centromere-Signaling Network Underlies the Coordination among Mitotic Events. Trivedi P, Stukenberg PT. Trends Biochem Sci. 2015 Dec 16. pii: S0968-0004(15)00210-8. doi: 10.1016/j.tibs.2015.11.002. PMID: 26705896

Identification of the posttranslational modifications present in centromeric chromatin. Bailey AO, Panchenko T, Shabanowitz J, Lehman SM, Bai DL, Hunt DF, Black BE, Foltz DR. Mol Cell Proteomics. 2015 Dec 18. pii: mcp.M115.053710. PMID: 26685127

GAGA factor maintains nucleosome-free regions and has a role in RNA polymerase II recruitment to promoters. Fuda NJ, Guertin MJ, Sharma S, Danko CG, Martins AL, Siepel A, Lis JT. PLoS Genet. 2015 Mar 27;11(3):e1005108. doi: 10.1371/journal.pgen.1005108. eCollection 2015 Mar. PMID: 25815464

Ethanolamine Signaling Promotes Salmonella Niche Recognition and Adaptation during Infection. Anderson CJ, Clark DE, Adli M, Kendall MM. PLoS Pathog. 2015 Nov 13;11(11):e1005278. doi: 10.1371/journal.ppat.1005278. eCollection 2015 Nov. PMID: 26565973

Genome-wide predictors of NF-κB recruitment and transcriptional activity. Cieślik M, Bekiranov S. BioData Min. 2015 Nov 26;8:37. eCollection 2015. PMID: 26617673

Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders. Brennand KJ, Marchetto MC, Benvenisty N, Brüstle O, Ebert A, Izpisua Belmonte JC, Kaykas A, Lancaster MA, Livesey FJ, McConnell MJ, McKay RD, Morrow EM, Muotri AR, Panchision DM, Rubin LL, Sawa A, Soldner F, Song H, Studer L, Temple S, Vaccarino FM, Wu J, Vanderhaeghen P, Gage FH, Jaenisch R. Stem Cell Reports. 2015 Nov 20. pii: S2213-6711(15)00308-2. doi: 10.1016/j.stemcr.2015.10.011. PMID: 26610635

Actin Polymerization is Stimulated by Actin Crosslinking Protein Palladin. Gurung R, Yadav R, Brungardt JG, Orlova A, Egelman EH, Beck MR. Biochem J. 2015 Nov 25. pii: BJ20151050. PMID: 26607837

Sequential replication-coupled destruction at G1/S ensures genome stability. Coleman KE, Grant GD, Haggerty RA, Brantley K, Shibata E, Workman BD, Dutta A, Varma D, Purvis JE, Cook JG. Genes Dev. 2015 Aug 15;29(16):1734-46. doi: 10.1101/gad.263731.115. Epub 2015 Aug 13. PMID: 26272819

Targeted H3R26 deimination specifically facilitates estrogen receptor binding by modifying nucleosome structure. Guertin MJ, Zhang X, Anguish L, Kim S, Varticovski L, Lis JT, Hager GL, Coonrod SA. PLoS Genet. 2014 Sep 11;10(9):e1004613. doi: 10.1371/journal.pgen.1004613. eCollection 2014 Sep.PMID: 25211228

DNA replication dynamics of the GGGGCC repeat of C9orf72.Thys RG, Wang YH. J Biol Chem. 2015 Oct 13. pii: jbc.M115.660324.PMID: 26463209

Ibrutinib interferes with the cell-mediated anti-tumor activities of therapeutic CD20 antibodies: implications for combination therapy. Da Roit F, Engelberts PJ, Taylor RP, Breij EC, Gritti G, Rambaldi A, Introna M, Parren PW, Beurskens FJ, Golay J. Haematologica. 2015 Jan;100(1):77-86. doi: 10.3324/haematol.2014.107011. Epub 2014 Oct 24. PMID: 25344523

Kif2a depletion generates chromosome segregation and pole coalescence defects in animal caps and inhibits gastrulation of the Xenopus embryo. Eagleson G, Pfister K, Knowlton AL, Skoglund P, Keller R, Stukenberg PT. Mol Biol Cell. 2015 Mar 1;26(5):924-37. doi: 10.1091/mbc.E13-12-0721. Epub 2015 Jan 7. PMID: 25568341

Structure and assembly of the mouse ASC inflammasome by combined NMR spectroscopy and cryo-electron microscopy. Sborgi L, Ravotti F, Dandey VP, Dick MS, Mazur A, Reckel S, Chami M, Scherer S, Huber M, Böckmann A, Egelman EH, Stahlberg H, Broz P, Meier BH, Hiller S. Proc Natl Acad Sci U S A. 2015 Oct 27;112(43):13237-42. doi: 10.1073/pnas.1507579112. Epub 2015 Oct 13. PMID: 26464513

Rad51 Paralogs Remodel Pre-synaptic Rad51 Filaments to Stimulate Homologous Recombination. Taylor MR, Špírek M, Chaurasiya KR, Ward JD, Carzaniga R, Yu X, Egelman EH, Collinson LM, Rueda D, Krejci L, Boulton SJ. Cell. 2015 Jul 16;162(2):271-86. doi: 10.1016/j.cell.2015.06.015. PMID: 26186187

Archaeal actin from a hyperthermophile forms a single-stranded filament. Braun T, Orlova A, Valegård K, Lindås AC, Schröder GF, Egelman EH. Proc Natl Acad Sci U S A. 2015 Jul 28;112(30):9340-5. doi: 10.1073/pnas.1509069112. Epub 2015 Jun 29. PMID: 26124094

Three-dimensional reconstruction of helical polymers. Egelman EH. Arch Biochem Biophys. 2015 Sep 1;581:54-8. doi: 10.1016/j.abb.2015.04.004. Epub 2015 Apr 22. Review. PMID: 25912526

Structural plasticity of helical nanotubes based on coiled-coil assemblies. Egelman EH, Xu C, DiMaio F, Magnotti E, Modlin C, Yu X, Wright E, Baker D, Conticello VP. Structure. 2015 Feb 3;23(2):280-9. doi: 10.1016/j.str.2014.12.008. Epub 2015 Jan 22. PMID: 25620001

The Xenopus ORFeome: A resource that enables functional genomics. Grant IM, Balcha D, Hao T, Shen Y, Trivedi P, Patrushev I, Fortriede JD, Karpinka JB, Liu L, Zorn AM, Stukenberg PT, Hill DE, Gilchrist MJ. Dev Biol. 2015 Sep 24. pii: S0012-1606(15)30172-X. doi: 10.1016/j.ydbio.2015.09.004. PMID: 26391338

Systems Analysis of Adaptive Responses to MAP Kinase Pathway Blockade in BRAF Mutant Melanoma. Capaldo BJ, Roller D, Axelrod MJ, Koeppel AF, Petricoin EF, Slingluff CL Jr, Weber MJ, Mackey AJ, Gioeli D, Bekiranov S. PLoS One. 2015 Sep 25;10(9):e0138210. doi: 10.1371/journal.pone.0138210. eCollection 2015. PMID: 26405815

Formaldehyde crosslinking: a tool for the study of chromatin complexes. Hoffman EA, Frey BL, Smith LM, Auble DT. J Biol Chem. 2015 Sep 9. pii: jbc.R115.651679. PMID: 26354429

Virology. A virus that infects a hyperthermophile encapsidates A-form DNA. DiMaio F, Yu X, Rensen E, Krupovic M, Prangishvili D, Egelman EH. Science. 2015 May 22;348(6237):914-7. doi: 10.1126/science.aaa4181. PMID: 25999507

Sequential replication-coupled destruction at G1/S ensures genome stability. Coleman KE, Grant GD, Haggerty RA, Brantley K, Shibata E, Workman BD, Dutta A, Varma D, Purvis JE, Cook JG. Genes Dev. 2015 Aug 15;29(16):1734-46. doi: 10.1101/gad.263731.115. Epub 2015 Aug 13. PMID: 26272819

Structural basis for recognition and remodeling of the TBP:DNA:NC2 complex by Mot1. Butryn A, Schuller JM, Stoehr G, Runge-Wollmann P, Förster F, Auble DT, Hopfner KP. Elife. 2015 Aug 10;4. doi: 10.7554/eLife.07432. PMID: 26258880

Protein Function Prediction: Problems and Pitfalls. Pearson WR. Curr Protoc Bioinformatics. 2015 Sep 3;51:4.12.1-8. doi: 10.1002/0471250953.bi0412s51.PMID: 26334923

A complex of p190RhoGAP-A and anillin modulates RhoA-GTP and the cytokinetic furrow in human cells. Manukyan A, Ludwig K, Sanchez-Manchinelly S, Parsons SJ, Stukenberg PT. J Cell Sci. 2015 Jan 1;128(1):50-60. doi: 10.1242/jcs.151647. Epub 2014 Oct 29. PMID: 25359885

Functional genomic analysis reveals overlapping and distinct features of chronologically long-lived yeast populations. Wierman MB, Matecic M, Valsakumar V, Li M, Smith DL Jr, Bekiranov S, Smith JS. Aging (Albany NY). 2015 Mar;7(3):177-94. PMID: 25769345

Environmental and chemotherapeutic agents induce breakage at genes involved in leukemia-causing gene rearrangements in human hematopoietic stem/progenitor cells. Thys RG, Lehman CE, Pierce LC, Wang YH. Mutat Res. 2015 Jun 27;779:86-95. doi: 10.1016/j.mrfmmm.2015.06.011. PMID: 26163765

Poly(Q) Expansions in ATXN7 Affect Solubility but Not Activity of the SAGA Deubiquitinating Module. Lan X, Koutelou E, Schibler AC, Chen YC, Grant PA, Dent SY. Mol Cell Biol. 2015 May;35(10):1777-87. doi: 10.1128/MCB.01454-14. Epub 2015 Mar 9. PMID: 25755283

MCM8-9 complex promotes resection of double-strand break ends by MRE11-RAD50-NBS1 complex. Lee KY, Im JS, Shibata E, Park J, Handa N, Kowalczykowski SC, Dutta A. Nat Commun. 2015 Jul 28;6:7744. doi: 10.1038/ncomms8744. PMID: 26215093

Discovery of CTCF-sensitive Cis-spliced fusion RNAs between adjacent genes in human prostate cells. Qin F, Song Z, Babiceanu M, Song Y, Facemire L, Singh R, Adli M, Li H. PLoS Genet. 2015 Feb 6;11(2):e1005001. doi: 10.1371/journal.pgen.1005001. eCollection 2015 Feb. PMID: 25658338

Assembly-driven activation of the AIM2 foreign-dsDNA sensor provides a polymerization template for downstream ASC. Morrone SR, Matyszewski M, Yu X, Delannoy M, Egelman EH, Sohn J. Nat Commun. 2015 Jul 22;6:7827. doi: 10.1038/ncomms8827. PMID: 26197926

Rad51 Paralogs Remodel Pre-synaptic Rad51 Filaments to Stimulate Homologous Recombination. Taylor MR, Špírek M, Chaurasiya KR, Ward JD, Carzaniga R, Yu X, Egelman EH, Collinson LM, Rueda D, Krejci L, Boulton SJ. Cell. 2015 Jul 16;162(2):271-86. doi: 10.1016/j.cell.2015.06.015. PMID: 26186187

The molecular basis for flexibility in the flexible filamentous plant viruses. DiMaio F, Chen CC, Yu X, Frenz B, Hsu YH, Lin NS, Egelman EH. Nat Struct Mol Biol. 2015 Jul 13. doi: 10.1038/nsmb.3054. PMID: 26167882

Production of Extrachromosomal MicroDNAs Is Linked to Mismatch Repair Pathways and Transcriptional Activity. Dillon LW, Kumar P, Shibata Y, Wang YH, Willcox S, Griffith JD, Pommier Y, Takeda S, Dutta A. Cell Rep. 2015 Jun 23;11(11):1749-59. doi: 10.1016/j.celrep.2015.05.020. Epub 2015 Jun 4. PMID: 26051933

Archaeal actin from a hyperthermophile forms a single-stranded filament. Braun T, Orlova A, Valegård K, Lindås AC, Schröder GF, Egelman EH. Proc Natl Acad Sci U S A. 2015 Jun 29. pii: 201509069.  PMID: 26124094

De novo protein structure determination from near-atomic-resolution cryo-EM maps. Wang RY, Kudryashev M, Li X, Egelman EH, Basler M, Cheng Y, Baker D, DiMaio F. Nat Methods. 2015 Apr;12(4):335-8. doi: 10.1038/nmeth.3287. Epub 2015 Feb 23. PMID: 25707029

Initiation of replication in Xenopus egg extracts at a spatially defined origin. Lee KY, Dutta A. Cell Cycle. 2015 Jun 19:0. No abstract available. PMID: 26091433

tRFdb: a database for transfer RNA fragments. Kumar P, Mudunuri SB, Anaya J, Dutta A. Nucleic Acids Res. 2015 Jan;43(Database issue):D141-5. doi: 10.1093/nar/gku1138. Epub 2014 Nov 11. PMID: 25392422

Cas9-chromatin binding information enables more accurate CRISPR off-target prediction. Singh R, Kuscu C, Quinlan A, Qi Y, Adli M. Nucleic Acids Res. 2015 Jun 1. pii: gkv575. PMID: 26032770

Most partial domains in proteins are alignment and annotation artifacts. Triant DA, Pearson WR. Genome Biol. 2015 May 15;16(1):99. doi: 10.1186/s13059-015-0656-7.PMID: 25976240

De novo mutations in SIK1 cause a spectrum of developmental epilepsies. Hansen J, Snow C, Tuttle E, Ghoneim DH, Yang CS, Spencer A, Gunter SA, Smyser CD, Gurnett CA, Shinawi M, Dobyns WB, Wheless J, Halterman MW, Jansen LA, Paschal BM, Paciorkowski AR. Am J Hum Genet. 2015 Apr 2;96(4):682-90. doi: 10.1016/j.ajhg.2015.02.013. PMID: 25839329

Virology. A virus that infects a hyperthermophile encapsidates A-form DNA. DiMaio F, Yu X, Rensen E, Krupovic M, Prangishvili D, Egelman EH. Science. 2015 May 22;348(6237):914-7. doi: 10.1126/science.aaa4181. PMID: 25999507

DNA secondary structure at chromosomal fragile sites in human disease. Thys RG, Lehman CE, Pierce LC, Wang YH. Curr Genomics. 2015 Feb;16(1):60-70. doi: 10.2174/1389202916666150114223205. PMID: 25937814

The acetyltransferase Tip60 is a critical regulator of the differentiation-dependent amplification of human papillomaviruses. Hong S, Dutta A, Laimins LA. J Virol. 2015 Apr;89(8):4668-75. doi: 10.1128/JVI.03455-14. Epub 2015 Feb 11. PMID: 25673709

The AAA+ proteins Pontin and Reptin enter adult age: from understanding their basic biology to the identification of selective inhibitors. Matias PM, Baek SH, Bandeiras TM, Dutta A, Houry WA, Llorca O, Rosenbaum J. Front Mol Biosci. 2015 May 5;2:17. doi: 10.3389/fmolb.2015.00017. eCollection 2015. PMID: 25988184

Disruption of the ran system by cysteine oxidation of the nucleotide exchange factor RCC1. Chatterjee M, Paschal BM. Mol Cell Biol. 2015 Feb;35(3):566-81. doi: 10.1128/MCB.01133-14. Epub 2014 Dec 1. PMID: 25452301

MUNC, a long noncoding RNA that facilitates the function of MyoD in skeletal myogenesis. Mueller AC, Cichewicz MA, Dey BK, Layer R, Reon BJ, Gagan JR, Dutta A. Mol Cell Biol. 2015 Feb;35(3):498-513. doi: 10.1128/MCB.01079-14. Epub 2014 Nov 17. PMID: 25403490

Structure of the type VI secretion system contractile sheath. Kudryashev M, Wang RY, Brackmann M, Scherer S, Maier T, Baker D, DiMaio F, Stahlberg H, Egelman EH, Basler M. Cell. 2015 Feb 26;160(5):952-62. doi: 10.1016/j.cell.2015.01.037. PMID: 25723169

PolyQ expansions in ATXN7 affect solubility but not activity of the SAGA deubiquitinating module. Lan X, Koutelou E, Schibler AC, Chen YC, Grant PA, Dent SY. Mol Cell Biol. 2015 Mar 9. pii: MCB.01454-14. PMID: 25755283.

Liu Y, Mayo MW, Xiao A, Hall EH, Amin EB, Kadota K, Adusumilli PS, Jones DR. Loss of BRMS1 promotes a mesenchymal phenotype through NF-κB-dependent regulation of Twist1. Mol Cell Biol. 2015 Jan;35(1):303-17. doi: 10.1128/MCB.00869-14. Epub 2014 Nov 3.PMID: 25368381.

Kudryashev M, Wang RY, Brackmann M, Scherer S, Maier T, Baker D, DiMaio F, Stahlberg H, Egelman EH, Basler M. Structure of the Type VI Secretion System Contractile Sheath. Cell. 2015 Feb 26;160(5):952-62. doi: 10.1016/j.cell.2015.01.037. PMID: 25723169

Wang RY, Kudryashev M, Li X, Egelman EH, Basler M, Cheng Y, Baker D, DiMaio F. De novo protein structure determination from near-atomic-resolution cryo-EM maps. Nat Methods. 2015 Feb 23. doi: 10.1038/nmeth.3287. PMID: 25707029

Disruption of the ran system by cysteine oxidation of the nucleotide exchange factor RCC1. Chatterjee M, Paschal BM. Mol Cell Biol. 2015 Feb;35(3):566-81. doi: 10.1128/MCB.01133-14. Epub 2014 Dec 1. PMID: 25452301

Regulation of the mitogen-activated protein kinase kinase (MEK)-1 by NAD(+)-dependent deacetylases. Yeung F, Ramsey CS, Popko-Scibor AE, Allison DF, Gray LG, Shin M, Kumar M, Li D, McCubrey JA, Mayo MW. Oncogene. 2015 Feb 5;34(6):798-804. doi: 10.1038/onc.2014.39. Epub 2014 Mar 31. PMID: 24681949

Structure of the type VI secretion system contractile sheath. Kudryashev M, Wang RY, Brackmann M, Scherer S, Maier T, Baker D, DiMaio F, Stahlberg H, Egelman EH, Basler M. Cell. 2015 Feb 26;160(5):952-62. doi: 10.1016/j.cell.2015.01.037. PMID: 25723169

Three-Dimensional Reconstruction of Helical Polymers. Egelman EH. Arch Biochem Biophys. 2015 Apr 22. pii: S0003-9861(15)00197-6. doi: 10.1016/j.abb.2015.04.004.  PMID: 25912526

MUNC, a long noncoding RNA that facilitates the function of MyoD in skeletal myogenesis. Mueller AC, Cichewicz MA, Dey BK, Layer R, Reon BJ, Gagan JR, Dutta A. Mol Cell Biol. 2015 Feb;35(3):498-513. doi: 10.1128/MCB.01079-14. Epub 2014 Nov 17. PMID: 25403490

Degree of Recruitment of DOT1L to MLL-AF9 Defines Level of H3K79 Di- and Tri-methylation on Target Genes and Transformation Potential. Kuntimaddi A, Achille NJ, Thorpe J, Lokken AA, Singh R, Hemenway CS, Adli M, Zeleznik-Le NJ, Bushweller JH. Cell Rep. 2015 Apr 21. pii: S2211-1247(15)00379-4. doi: 10.1016/j.celrep.2015.04.004. PMID: 25921540

Connecting the microtubule attachment status of each kinetochore to cell cycle arrest through the spindle assembly checkpoint. Stukenberg PT, Burke DJ. Chromosoma. 2015 Apr 28. PMID: 25917595

Fcγ-receptor-mediated trogocytosis impacts mAb-based therapies: historical precedence and recent developments. Taylor RP, Lindorfer MA. Blood. 2015 Jan 29;125(5):762-6. doi: 10.1182/blood-2014-10-569244. Epub 2014 Dec 10. PMID: 25498911

Functional genomic analysis reveals overlapping and distinct features of chronologically long-lived yeast populations. Weirman MB, Matecic M, Valsakumar V, Li M, Smith DL Jr, Bekiranov S, Smith JS. Aging (Albany NY). 2015 Mar 7. MID: 25769345

De Novo Mutations in SIK1 Cause a Spectrum of Developmental Epilepsies. Hansen J, Snow C, Tuttle E, Ghoneim DH, Yang CS, Spencer A, Gunter SA, Smyser CD, Gurnett CA, Shinawi M, Dobyns WB, Wheless J, Halterman MW, Jansen LA, Paschal BM, Paciorkowski AR. Am J Hum Genet. 2015 Apr 2;96(4):682-90. doi: 10.1016/j.ajhg.2015.02.013. PMID: 25839329

Activin upregulation by NF-κB is required to maintain mesenchymal features of cancer stem-like cells in non-small cell lung cancer. Wamsley JJ, Kumar M, Allison DF, Clift SH, Holzknecht CM, Szymura SJ, Hoang SA, Xu X, Moskaluk CA, Jones DR, Bekiranov S, Mayo MW. Cancer Res. 2015 Jan 15;75(2):426-35. doi: 10.1158/0008-5472.CAN-13-2702. Epub 2014 Nov 28. PMID: 25432175

PolyQ expansions in ATXN7 affect solubility but not activity of the SAGA deubiquitinating module. Lan X, Koutelou E, Schibler AC, Chen YC, Grant PA, Dent SY. Mol Cell Biol. 2015 Mar 9. pii: MCB.01454-14. PMID: 25755283

Qin F, Song Z, Babiceanu M, Song Y, Facemire L, Singh R, Adli M, Li H. Discovery of CTCF-Sensitive Cis-Spliced Fusion RNAs between Adjacent Genes in Human Prostate Cells. PLoS Genet. 2015 Feb 6;11(2):e1005001. doi: 10.1371/journal.pgen.1005001. eCollection 2015 Feb. PMID: 25658338

Sakurai K, Reon BJ, Anaya J, Dutta A. The lncRNA DRAIC/PCAT29 locus constitutes a tumor suppressive nexus. Mol Cancer Res. 2015 Feb 20. pii: molcanres.0016.2015. PMID: 25700553

Hong S, Dutta A, Laimins LA. The acetyltransferase Tip60 is a critical regulator of the differentiation-dependent amplification of human papillomaviruses. J Virol. 2015 Feb 11. pii: JVI.03455-14. PMID: 25673709

Yeung F, Ramsey CS, Popko-Scibor AE, Allison DF, Gray LG, Shin M, Kumar M, Li D, McCubrey JA, Mayo MW. Regulation of the mitogen-activated protein kinase kinase (MEK)-1 by NAD(+)-dependent deacetylases. Oncogene. 2015 Feb 5;34(6):798-804. doi: 10.1038/onc.2014.39. Epub 2014 Mar 31. PubMed PMID:24681949; PubMed Central PMCID: PMC4182313.

Chatterjee M, Paschal BM. Disruption of the Ran System by Cysteine Oxidation of the Nucleotide Exchange Factor RCC1. Mol Cell Biol. 2015 Feb 1;35(3):566-81. doi: 10.1128/MCB.01133-14. Epub 2014 Dec 1. PubMed PMID: 25452301; PubMed Central PMCID: PMC4285427.

Mueller AC, Cichewicz MA, Dey BK, Layer R, Reon BJ, Gagan JR, Dutta A. MUNC, a Long Noncoding RNA That Facilitates the Function of MyoD in Skeletal Myogenesis. Mol Cell Biol. 2015 Feb 1;35(3):498-513. doi: 10.1128/MCB.01079-14. Epub 2014 Nov 17.  PubMed PMID: 25403490; PubMed Central PMCID: PMC4285423.

Taylor RP, Lindorfer MA. FcŒ≥-receptor-mediated trogocytosis impacts mAb-based therapies: historical precedence and recent developments. Blood. 2015 Jan 29;125(5):762-766. Epub 2014 Dec 10. Review. PubMed PMID: 25498911.

Kumar P, Mudunuri SB, Anaya J, Dutta A. tRFdb: a database for transfer RNA fragments. Nucleic Acids Res. 2015 Jan 28;43(Database issue):D141-5. doi:10.1093/nar/gku1138. Epub 2014 Nov 11. PubMed PMID: 25392422.

Wamsley JJ, Kumar M, Allison DF, Clift SH, Holzknecht CM, Szymura SJ, Hoang SA, Xu X, Moskaluk CA, Jones DR, Bekiranov S, Mayo MW. Activin Upregulation by NF-Œ∫B Is Required to Maintain Mesenchymal Features of Cancer Stem-like Cells in Non-Small Cell Lung Cancer. Cancer Res. 2015 Jan 15;75(2):426-35. doi: 10.1158/0008-5472.CAN-13-2702. Epub 2014 Nov 28. PubMed PMID: 25432175; PubMed Central PMCID: PMC4297542.

Galkin VE, Orlova A, Vos MR, Schr√∂der GF, Egelman EH. Near-atomic resolution for one state of f-actin. Structure. 2015 Jan 6;23(1):173-82. doi: 10.1016/j.str.2014.11.006. Epub 2014 Dec 18. PubMed PMID: 25533486; PubMed Central PMCID: PMC4286464.

Roit FD, Engelberts PJ, Taylor RP, Breij EC, Gritti G, Rambaldi A, Introna M, Parren PW, Beurskens FJ, Golay J. Ibrutinib interferes with the cell-mediated anti-tumor activities of therapeutic CD20 antibodies: implications for combination therapy. Haematologica. 2015 Jan;100(1):77-86. doi: 10.3324/haematol.2014.107011. Epub 2014 Oct 24. PubMed PMID: 25344523; PubMed Central PMCID: PMC4281316.

Manukyan A, Ludwig K, Sanchez-Manchinelly S, Parsons SJ, Stukenberg PT. A complex of p190RhoGAP-A and anillin modulates RhoA-GTP and the cytokinetic furrow in human cells. J Cell Sci. 2015 Jan 1;128(1):50-60. doi: 10.1242/jcs.151647. Epub 2014 Oct 29. PubMed PMID: 25359885; PubMed Central PMCID: PMC4282047.

Liu Y, Mayo MW, Xiao A, Hall EH, Amin EB, Kadota K, Adusumilli PS, Jones DR. Loss of BRMS1 promotes a mesenchymal phenotype through NF-Œ∫B-dependent regulation of Twist1. Mol Cell Biol. 2015 Jan;35(1):303-17. doi: 10.1128/MCB.00869-14. Epub 2014 Nov 3. PubMed PMID: 25368381; PubMed Central PMCID: PMC4295387.

Cox KH, Quinnies KM, Eschendroeder A, Didrick PM, Eugster EA, Rissman EF. Number of X-chromosome genes influences social behavior and vasopressin gene expression in mice. Psychoneuroendocrinology. 2015 Jan;51:271-81. doi: 10.1016/j.psyneuen.2014.10.010. Epub 2014 Oct 23. PubMed PMID: 25462900.