Histone modifications lead to structural changes in chromatin or the recruitment of effector proteins, which can regulate gene expression, DNA repair and replication. This team is involved in the characterization of such epigenetic changes associated with either cancer or neurodegenerative disease.
Transcription; Chromatin Modifications, Neurodegenerative Disease, Cancer
Mechanisms of Brain Astroglial Activation in Neural Injury
David R. Jones, Chief of Thoracic Surgery, Memorial Sloan Kettering Cancer Center
Sharon Y.R. Dent, Professor & Chair, Department of Epigenetics and Molecular Carcinogenesis and Director of The Virginia Harris Cockrell Cancer Research Center at Science Park & Center of Epigenetics, The University of Texas MD Anderson Cancer Center, Smithville, TX.